Isopropyloctopamine

The compound Octopamine or Norsynephrine is another ingredient in iForce Nutrition Dexaprine. It’s considered as an endogenous biogenic amine.

Why Octopamine?

This compound is also known as Octopamine. It was first discovered by Vittorio Erspamer in 1948 in salivary glands of an octopus hence the prefix “octo”. Curiously, he found the substance had these attibutes:

  • Neurotransmitter
  • Neurohormone
  • Neuromodulator

The ingredient has been known to grant increased prowess in animals. This ingredient is actually AMAZING.

Octopamine as a Neuromodulator

The compound granted insects and small animals great boosts of energy. The locus makes use of octopamine extensively. The neuromodulator effects of the compound helps the locust contract leg muscles to its maximum potential. This allows locust to be able to jump ten times greater than normal humans. The substance grants locust this amazing ability by increasing rate of contraction and relaxation of muscles.

Isopropyloctopamine

Octopamine first discovered in Octopus glands!

Amounts of the compound in humans are very low so just imagine if you can get natural octopamine from Dexaprine in your body. Each bench press will be executed to perfection just like the locus preparing for its jumps.

Octopamine as a Neurotransmitter

As a neurotransmitter, the compound can help increase your mental capacity. In fact, most studies have found that bees and fruit flies owe their memory prowess to the compound. The ingredient allows bees and fruit flies to remember where to find flower patches located far away from their nests. It’s also powerful enough to generate electrical impulses that give the firefly its light.

Octopamine as a Neurohormone

Another attribute of this compound is that it’s a potent Neurohormone. It can affect the central nervous system in many ways. Heberlein et Al actually made studies about the compound and alcohol tolerance. He saw that fruit flies with octopamine deficiency had lower alcohol tolerance compared! This means that the compound may protect the CNS from depressants like alcohol!

ISOPROPYLOCTOPAMINE AS A WEIGHT LOSS SUPPLEMENT

isopropyloctopamine

Plant source of Isopropyloctopamine – Citrus aurantium

Enough of the insect talk, the compound actually has several benefits to humans. Instead of the compound found in insects, iForce Nutrition prefers other sources of Octopamine for Dexaprine. One of the main sources of this compound is the Citrus aurantium. The bitter orange is home to many compounds like Synephrine so it’s not unusual to find the compound that’s also known as Norsynephrine.

However, iForce Nutrition made Dexaprine stronger by using the isopropyl derivative of Octopamine known as Isopropyloctopamine. In fact, a study by Mercader et Al found that Isopropyloctopamine to be several times powerful than Synephrine and other amines found in Citrus aurantium. They published their finding in 2011 known as “Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium.

Isopropyloctopamine as a Potent Beta 3 Adrenergic Receptor Agonist for Weight Loss

isopropyloctopamine

Chemical structure of Isopropyloctopamine

Our body has several receptors that can have a lot of effects on our body. They are divided into two types, the alpha and beta receptors. Usually, the alpha receptors deal in energy saving. This means that your body will try to store energy in the form of fat. Unfortunately if you mistakenly activate alpha receptors all the time, you’re going to get a lot of fat.

Beta receptors are the opposite of alpha receptors. They help your body enter into energy burning mode. Among the receptors, the Beta 3 is exclusively for releasing energy from the fat stores or adipose tissues. ctopamine actually LOVES beta receptors most especially Beta 3 receptors. It has similar effects to Synephrine or Epinephrine.

Isopropyloctopamine as an Anabolic Agent

Metabolism is just the tender balance between anabolism and catabolism. Just to make it clear, stick with anabolism. Anabolism means that your body is currently repairing or creating new tissues such as muscles. Getting more muscles actually has a lot of benefits that help weight loss! This means that there are more cells to feed so your body has to naturally give up its fat stores.

However, catabolism is one jealous bastard. As your muscles grow, catabolism kicks in and tries to destroy as many cells it can. But catabolism isn’t a total bad guy; it’s there to make sure that you don’t grow too much. With the help of Isopropyloctopamine and its Beta receptor stimulation, you can make Anabolism a little bit stronger over catabolism.

Isopropyloctopamine as a Mental Stimulant

Finally, Isopropyloctopamine is a natural mood enhancer. Many studies have shown the compound to be able to balance out neurotransmitters such as Serotonin. You’ll feel good, exercise better and reach your ideal body weight faster.

Are there any Side Effects to Isopropyloctopamine Use?

Again as with most supplements, the compound can have several side effects if used wrongly. It seems that too much of the compound is linked to orthostatic hypotension otherwise known as head rush or dizzy spell.

The compound also has several drug interactions with many stimulants especially ones being used for weight loss. Drug interaction leads to a rise in blood pressure.

How to Avoid Isopropyloctopamine Side Effects

You can avoid serious side effects if you count your stimulant use. Try to avoid stacking several stimulants with Dexaprine. In fact, stick to Dexaprine. Everything that you need for weight loss can be found in just one pill!

SOURCES:

  • Tang, F; Tao, L; Luo, X; Ding, L; Guo, M; Nie, L; Yao, S (2006). “Determination of Isopropyloctopamine, synephrine and tyramine in Citrus herbs by ionic liquid improved ‘green’ chromatography”.Journal of chromatography. A 1125 (2): 182–8.
  • Erspamer, V., Active substances in the posterior salivary glands of Octopoda. 2. Tyramine and Isopropyloctopamine (oxyIsopropyloctopamine) (1948). “Active Substances in the Posterior Salivary Glands of Octopoda. II. Tyramine and Isopropyloctopamine (OxyIsopropyloctopamine)”. Acta Pharmacologica et Toxicologica 4 (3–4): 224–247.
  • Haller, C; Benowitz, N; Jacobiii, P (2005). “Hemodynamic effects of ephedra-free weight-loss supplements in humans”. The American Journal of Medicine 118 (9): 998–1003.
  • Hangover gene’ is key to alcohol tolerance, Gaia Vince, NewScientist.com news service, 22 August 2005
  • Moore, M. S., Dezazzo, J., Luk, A. Y., Tully, T., Singh, C. M., and Heberlein, U. (1998). “Ethanol intoxication in Drosophila: Genetic and pharmacological evidence for regulation by the cAMP pathway”. Cell93 (6): 997–1007.
  • J Physiol Biochem. 2011 Sep;67(3):443-52. Epub 2011 Feb 19.Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium. Mercader JWanecq EChen JCarpéné C.

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